Anglais
Arabic
Laure CHAMY (EL)
Faculté des sciences – Professeur associé
+961 (1) 421 000 ext 3485 laure.chamy@usj.edu.lb
Laure El Chamy est Professeur associé à la Faculté des sciences de l’Université Saint-Joseph de Beyrouth et la coordinatrice du Master en « Génomique et Protéomique Fonctionnelles ». Elle est titulaire d’un doctorat en « Biologie moléculaire et Cellulaire » de l’Université de Strasbourg. Au cours de sa formation doctorale au sein du Laboratoire « Modèles Insectes d’Immunité Innée », elle a développé une expertise dans l'étude génétique de l'immunité innée utilisant le modèle Drosophila melanogaster.Ses intérêts de recherche se concentrent sur la caractérisation des interactions hôtes- pathogènes, avec un intérêt particulier pour les bactéries du groupe Bacillus cereus. Elle est également impliquée dans l'identification des espèces par la méthode du DNA barcoding, dans le cadre d'une stratégie visant à surveiller et préserver la biodiversité. Elle a reçu plusieurs prix et distinctions, dont le financement du programme International « L’Oréal- UNSECO pour les femmes et la science 2013. En 2014, elle a été nommée au programme “Women in science hall of Fame” de l’ambassade des Etats- Unis à Beyrouth puis au programme « International Visitor Leadership Program- IVLP 2015» pour participer au projet « Women in Sciences Technology Engineering and Mathematics (STEM) fields ».
Education
| Diplôme | Université | Pays | Année |
|---|---|---|---|
| Doctorat de Biologie Moléculaire et Cellulaire | Université de Strasbourg | France | 2008 |
| D.E.A Biologie Cellulaire et Moléculaire | Université de Strasbourg | France | 2004 |
| Maitrise en Sciences de la vie et de la terre | Saint Joseph University of Beyrouth | Liban | 2003 |
Enseignement à l'USJ
Enseignement universitaire hors USJ
| Enseignement universitaire hors USJ | Pays | Etablissement | Date début | Date fin |
|---|---|---|---|---|
| TD Licence sciences du vivant | France | Université de Strasbourg | 01/11/2006 | 15/12/2006 |
| TD UE Dynamique et Regulation | France | Université de Strasbourg | 02/10/2006 | 30/10/2006 |
| TD UE Dynamique et Regulation | France | Université de Strasbourg | 01/11/2005 | 31/01/2018 |
| TD Biologie cellulaire | France | Université de Strasbourg | 10/10/2005 | 31/10/2005 |
Expérience professionnelle hors USJ
Domaine d’expertise
Thématiques de recherche
<span lang="FR" style="font-size:10.0pt;font-family:" times="" new="" roman",serif;mso-fareast-font-family:"times="" roman";mso-ansi-language:="" fr;mso-fareast-language:en-us;mso-bidi-language:ar-sa;layout-grid-mode:line"="">Interactionhôte- pathogène, modèle <i>Drosophila melanogaster- Bacillus cereus/thuringiensis </i></span>
Publications et communications
<p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">The NF-κB factor Relishis essential for the epithelial defenses protecting against δ-endotoxindependent effects of Bacillus thuringiensis israelensis infection in theDrosophila model. <span style="mso-spacerun:yes"> </span></span><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">Mouawad C, Kallassy AwadM, Liegeois S, Ferrandon D, Sanchis-Borja V and </span><b style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">El Chamy L</b><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">. Research inmicrobiology.2023</span></p><p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">The PP4 phosphatasenegatively regulates the IMD-NF-kB pathway during the Drosophila immuneresponse.</span><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">Salem Wehbeh L, BarakatD, Acker A, El Khoury R, Reichhart JM, Matt N and </span><b style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">El Chamy L</b><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">. J.Immunology. 2021</span></p><p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">The </span><i style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">fliK </i><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">Gene IsRequired for the Resistance of </span><i style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">Bacillus thuringiensis</i><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;"> to AntimicrobialPeptides and Virulence in </span><i style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">Drosophila melanogaster</i><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">. </span><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">Attieh Z, Mouawad C,Rejasse A, Jehanno I, Perchat S, Hegna IK, Økstad OA, Kallassy Awad M, Sanchis-BorjaV and </span><b style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">El Chamy L</b><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">. Frontiers in Microbiology. 2020 Dec 1</span></p><p class="MsoNormal" style="text-align:justify;line-height:115%"></p><p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">DltX of Bacillusthuringiensis is essential for D-alanylation of teichoic acids and forresistance to the humoral antimicrobial responses in insects. <o:p></o:p></span></p><p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">Kamar R, Réjasse A, JéhannoI, Attieh Z, Courtin P, Chapot-Chartier MP, Nielsen-Leroux C, Lereclus D, <b>ElChamy L</b>, Kallassy M and Sanchis-Borja V. Front Microbiol. 2017 Aug 3;8:1437<o:p></o:p></span></p><p class="MsoNormal" style="line-height:115%"><span style="font-size: 11pt; line-height: 115%; font-family: Corbel, sans-serif; color: rgb(34, 42, 53);">Advances in Myeloid-LikeCell Origins and Functions in the Model Organism <i>Drosophila melanogaster</i>. </span><b><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">El Chamy L</span></b><span style="font-size: 11pt; line-height: 115%; font-family: Corbel, sans-serif; color: rgb(34, 42, 53);">, Matt N and ReichhartJM. Microbiol Spectr. 2017. Jan; 5 (1).</span></p><p class="MsoNormal" style="line-height:115%"><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">The multilayered innateimmune defense of the gut. </span><b><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">El Chamy L</span></b><span style="font-size: 11pt; line-height: 115%; font-family: Corbel, sans-serif; color: rgb(34, 42, 53);">, Matt N, Ntwasa M and ReichhartJM. Biomed J 2015; 38:276-284</span></p><p class="MsoNormal" style="line-height: 115%;"><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">Invertebrate InnateImmune Defenses. <o:p></o:p></span></p><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;"></span><p></p><p class="MsoNormal" style="line-height:115%"><span style="font-size: 11pt; line-height: 115%; font-family: Corbel, sans-serif; color: rgb(34, 42, 53);"></span></p><p class="MsoNormal" style="text-align:justify;line-height:115%"><b><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">El Chamy L</span></b><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">, Hetru C and HoffmannJA. Chapter one of “The immune response to infection”, edited by Stefan H.E.Kaufmann, Barry T. Rouse and David L. Sacks. </span><span lang="FR" style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128;mso-ansi-language:fr"="">ASMpress- Washington DC. Copyright 2011.</span></p><p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">Sensing of dangersignals and pathogen-associated molecular patterns defines binary signalingpathways upstream of Toll. <b>El Chamy L</b>, Leclerc V, Caldelari Iand ReichhartJM. Nat Immunol. 2008 Oct ;9(10) :1165-1170. <o:p></o:p></span></p><p class="MsoNormal" style="text-align:justify;line-height:115%"><span style="font-size: 11pt; line-height: 115%; font-family: Corbel, sans-serif; color: rgb(34, 42, 53);">Akirins, highlyconserved nuclear proteins, required for NF-κB dependent gene expression inDrosophila and mice.</span><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">Goto A, Matsushita K, GesellchenV, </span><b style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">El Chamy L</b><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;">, Kuttenkeuler D, Takeuchi O, Hoffmann JA, Akira S, BoutrosM & Reichhart JM. Nat Immunol. 2008 Feb;9(2):216.</span><span style="color: rgb(34, 42, 53); font-family: Corbel, sans-serif; font-size: 11pt;"> </span></p>