Laure CHAMY (EL)

Faculté des sciences – Professeur associé

+961 (1) 421 000 ext 3485 laure.chamy@usj.edu.lb

Laure El Chamy is an Associate Professor at the Faculty of Sciences- Saint-Joseph University of Beirut and the coordinator of the Master in « Functional Genomics and Proteomics ». She holds a PhD in “Molecular and Cellular Biology” from the University of Strasbourg. During her doctoral training at the laboratory of Insect models for Innate Immunity, she developed expertise in genetic analysis of innate immunity using the Drosophila melanogaster model. Her research interests focus on the characterization of host-pathogen interactions with a particular interest in the Bacillus cereus group. She is also involved in species identification through DNA barcoding as part of a strategy to monitor and preserve biodiversity. She has received several awards and distinctions, including the “L’Oréal- UNESCO for women in science”- international fellowship program 2013. In 2014, she was nominated to the “Women in science hall of fame program” of the US embassy in Beirut and the following year she was nominated to the « International Visitor Leadership Program- IVLP» to participate in the project « Women in Sciences Technology Engineering and Mathematics (STEM) fields ».

Education

Diplôme	Université	Pays	Année
PHD Molecular and Cellular Biology	Université de Strasbourg	France	2008
DEA in Cellular and Molecular Biology	Université de Strasbourg	France	2004
Maitrise en Sciences de la vie et de la terre	Saint Joseph University of Beyrouth	Lebanon	2003

Teaching at USJ

048GEGBL2<div>048GFMBL3</div><div>048IMMBL5</div><div>048GGCBM1</div><div>048ICTBM1</div><div>048GACBM2</div><div>048GPCBM3</div><div>048RICBM3</div><div>048SASBM3</div>

University teaching outside USJ

University teaching outside USJ	Pays	Institution	Start date	End date

Professional experience outside USJ

Areas of expertise

Engineering and Technology, Sciences

Research themes

<span lang="FR" style="font-size:10.0pt;font-family:" times="" new="" roman",serif;mso-fareast-font-family:"times="" roman";mso-ansi-language:="" fr;mso-fareast-language:en-us;mso-bidi-language:ar-sa;layout-grid-mode:line"="">Interactionhôte- pathogène, modèle Drosophila melanogaster- Bacillus cereus/thuringiensis

Publications and communications

<span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">The NF-κB factor Relishis essential for the epithelial defenses protecting against δ-endotoxindependent effects of Bacillus thuringiensis israelensis infection in theDrosophila model.  Mouawad C, Kallassy AwadM, Liegeois S, Ferrandon D, Sanchis-Borja V and El Chamy L. Research inmicrobiology.2023The PP4 phosphatasenegatively regulates the IMD-NF-kB pathway during the Drosophila immuneresponse.Salem Wehbeh L, BarakatD, Acker A, El Khoury R, Reichhart JM, Matt N and El Chamy L. J.Immunology. 2021The fliK Gene IsRequired for the Resistance of Bacillus thuringiensis to AntimicrobialPeptides and Virulence in Drosophila melanogaster. Attieh Z, Mouawad C,Rejasse A, Jehanno I, Perchat S, Hegna IK, Økstad OA, Kallassy Awad M, Sanchis-BorjaV and El Chamy L. Frontiers in Microbiology. 2020 Dec 1<span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">DltX of Bacillusthuringiensis is essential for D-alanylation of teichoic acids and forresistance to the humoral antimicrobial responses in insects. <o:p></o:p><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">Kamar R, Réjasse A, JéhannoI, Attieh Z, Courtin P, Chapot-Chartier MP, Nielsen-Leroux C, Lereclus D, ElChamy L, Kallassy M and Sanchis-Borja V. Front Microbiol. 2017 Aug 3;8:1437<o:p></o:p>Advances in Myeloid-LikeCell Origins and Functions in the Model Organism Drosophila melanogaster. <span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">El Chamy L, Matt N and ReichhartJM. Microbiol Spectr. 2017. Jan; 5 (1).The multilayered innateimmune defense of the gut. <span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">El Chamy L, Matt N, Ntwasa M and ReichhartJM. Biomed J 2015; 38:276-284<span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">Invertebrate InnateImmune Defenses. <o:p></o:p><span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">El Chamy L<span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">, Hetru C and HoffmannJA. Chapter one of “The immune response to infection”, edited by Stefan H.E.Kaufmann, Barry T. Rouse and David L. Sacks. <span lang="FR" style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128;mso-ansi-language:fr"="">ASMpress- Washington DC. Copyright 2011.<span style="font-size:11.0pt;mso-bidi-font-size:12.0pt;line-height:115%;font-family:" corbel",sans-serif;mso-bidi-font-family:calibri;mso-bidi-theme-font:minor-latin;="" color:#222a35;mso-themecolor:text2;mso-themeshade:128"="">Sensing of dangersignals and pathogen-associated molecular patterns defines binary signalingpathways upstream of Toll. El Chamy L, Leclerc V, Caldelari Iand ReichhartJM. Nat Immunol. 2008 Oct ;9(10) :1165-1170. <o:p></o:p>Akirins, highlyconserved nuclear proteins, required for NF-κB dependent gene expression inDrosophila and mice.Goto A, Matsushita K, GesellchenV, El Chamy L, Kuttenkeuler D, Takeuchi O, Hoffmann JA, Akira S, BoutrosM & Reichhart JM. Nat Immunol. 2008 Feb;9(2):216.

Laure CHAMY (EL)

Faculté des sciences – Professeur associé

Education

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