French
Arabic
Laure CHAMY (EL)
Associate Professor
Faculty of Medicine – Chargé de Cours
Faculty of Science – Chef de département Sciences de la vie et de la terre - biochimie
+961 (1) 421 000 ext 3485 laure.chamy@usj.edu.lb
Laure El Chamy is an Associate Professor at the Faculty of Sciences- Saint-Joseph University of Beirut and the coordinator of the Master in « Functional Genomics and Proteomics ». She holds a PhD in “Molecular and Cellular Biology” from the University of Strasbourg. During her doctoral training at the laboratory of Insect models for Innate Immunity, she developed expertise in genetic analysis of innate immunity using the Drosophila melanogaster model. Her research interests focus on the characterization of host-pathogen interactions with a particular interest in the Bacillus cereus group. She is also involved in species identification through DNA barcoding as part of a strategy to monitor and preserve biodiversity. She has received several awards and distinctions, including the “L’Oréal- UNESCO for women in science”- international fellowship program 2013. In 2014, she was nominated to the “Women in science hall of fame program” of the US embassy in Beirut and the following year she was nominated to the « International Visitor Leadership Program- IVLP» to participate in the project « Women in Sciences Technology Engineering and Mathematics (STEM) fields ».
Education
| Degree | University | Country | Year |
|---|---|---|---|
| PHD Molecular and Cellular Biology | Université de Strasbourg | France | 2008 |
| DEA in Cellular and Molecular Biology | Université de Strasbourg | France | 2004 |
| Maitrise en Sciences de la vie et de la terre | Saint Joseph University of Beyrouth | Lebanon | 2003 |
Teaching at USJ
Areas of expertise
Research themes
Publications and communications
The NF-κB factor Relishis essential for the epithelial defenses protecting against δ-endotoxindependent effects of Bacillus thuringiensis israelensis infection in theDrosophila model. Mouawad C, Kallassy AwadM, Liegeois S, Ferrandon D, Sanchis-Borja V and El Chamy L. Research inmicrobiology.2023
The PP4 phosphatasenegatively regulates the IMD-NF-kB pathway during the Drosophila immuneresponse.Salem Wehbeh L, BarakatD, Acker A, El Khoury R, Reichhart JM, Matt N and El Chamy L. J.Immunology. 2021
The fliK Gene IsRequired for the Resistance of Bacillus thuringiensis to AntimicrobialPeptides and Virulence in Drosophila melanogaster. Attieh Z, Mouawad C,Rejasse A, Jehanno I, Perchat S, Hegna IK, Økstad OA, Kallassy Awad M, Sanchis-BorjaV and El Chamy L. Frontiers in Microbiology. 2020 Dec 1
DltX of Bacillusthuringiensis is essential for D-alanylation of teichoic acids and forresistance to the humoral antimicrobial responses in insects.
Kamar R, Réjasse A, JéhannoI, Attieh Z, Courtin P, Chapot-Chartier MP, Nielsen-Leroux C, Lereclus D, ElChamy L, Kallassy M and Sanchis-Borja V. Front Microbiol. 2017 Aug 3;8:1437
Advances in Myeloid-LikeCell Origins and Functions in the Model Organism Drosophila melanogaster. El Chamy L, Matt N and ReichhartJM. Microbiol Spectr. 2017. Jan; 5 (1).
The multilayered innateimmune defense of the gut. El Chamy L, Matt N, Ntwasa M and ReichhartJM. Biomed J 2015; 38:276-284
Invertebrate InnateImmune Defenses.
El Chamy L, Hetru C and HoffmannJA. Chapter one of “The immune response to infection”, edited by Stefan H.E.Kaufmann, Barry T. Rouse and David L. Sacks. ASMpress- Washington DC. Copyright 2011.
Sensing of dangersignals and pathogen-associated molecular patterns defines binary signalingpathways upstream of Toll. El Chamy L, Leclerc V, Caldelari Iand ReichhartJM. Nat Immunol. 2008 Oct ;9(10) :1165-1170.
Akirins, highlyconserved nuclear proteins, required for NF-κB dependent gene expression inDrosophila and mice.Goto A, Matsushita K, GesellchenV, El Chamy L, Kuttenkeuler D, Takeuchi O, Hoffmann JA, Akira S, BoutrosM & Reichhart JM. Nat Immunol. 2008 Feb;9(2):216.