The Role of Gut Dysbiosis in Kidney Injury Using the DSS Model in Rats

Description :
Much of the existing research has focused on the bacterial translocations and toxins in the context of AKI or CKD, with few studies exploring the mechanisms of kidney injury mediated by gut dysbiosis. In Vivo study: confirmation of gut dysbiosis inductiojn. Renal histology. Renal bacterial translocation: NGS screening on renal tissue. Molecular analysis of renal tissue: antibody array for inflammation signaling pathways. In Vitro Study: Cell proliferation and viability. Molecular analysis: antibody array for inflammation signaling pathways.

Titulaire :
KOTAIT NASSEH Micheline Mia

Contact USJ :
michelinemia.kotait1@usj.edu.lb

Chercheur(s) :
Dr Micheline Mia KOTAIT, Dr Nassim FARES, M. Youakim SALIBA

Projet présenté au CR, le : 02/01/2025

Projet achevé auprès du CR : 31/12/2025