Marianne ABI FADEL

أستاذ
Directeur - ETLAM - مَدْرَسَة التَّحْضِير المَخْبَرِيّ الطِّبّي

كُلِّيّة الصَّيْدَلة
مختبرات رودولف ميريو - لبنان
Directeur

+961 (1) 421 000 تحويلة 2233 marianne.abifadel@usj.edu.lb

Marianne Abi Fadel is the elected Dean of the School of Pharmacy at USJ since 2013, the director of the laboratory of Biochemistry Molecular Therapeutics (LBTM) at the School of Pharmacy, a professor of biochemistry molecular biology at USJ. She is also an invited researcher at INSERM U1148 at Bichat hospital Paris Cité University in Paris, the director of the Laboratory Rodolphe Mérieux in Lebanon since 2018 providing diagnosis to migrants vulnerable populations.She obtained her Pharmacy Diploma in 1996, her Laboratory Medicine Clinical Biochemistry Specialization Diploma from USJ, then her PhD in Molecular Genetics in 2003 the French accreditation to supervise research in 2009 from the University of Paris-Descartes. Her main scientific achievement is the discovery of the implication of PCSK9 in Familial Hypercholesterolemia by identifying its first gain of function (GOF) mutations (Abifadel et al. Nature Genetics 2003). This was the seminal paper linking PCSK9 to cholesterol metabolism was the starting point of the PCSK9 adventure from gene to a new therapeutic class: the anti-PCSK9.With several publications in journals with high impact factor (ex: 3 in Nature Genetics IF41, 3 in The Lancet IF168…), she was awarded several national international distinctions for her work on Familial Hypercholesterolemia FH notably: - The Chancellery of Paris Universities: Nathalie Demassieux prize in 2004,- the CNRS-L (National Council for Scientific Research, Lebanon) Award in Recognition of Distinguished Scientific Researchers in 2012, - the ‘Société des Membres de la Légion d’honneur’ Scientific Excellence Award in 2016, - the prestigious Christophe Mérieux Prize 2021 from the “Institute de France” in Paris - the Golden Award of the Italian Society of Atherosclerosis in 2022. She is a Principal Investigator of several working groups, invited speaker in international scientific meetings member of advisory boards. She is an elected member in the National French Academy of Pharmacy as international correspondent since 2019 honored with the Medal of the French National Academy of Pharmacy, National Lead of Lebanon at EAS-FHSC Member of the International Society of Atherosclerosis representing MENA region, member of the Saint Joseph University of Beirut HDF hospital government boards.

محاور البحث

Her research focuses on PCSK9, the genetics of Familial Hypercholesterolemia (FH), dyslipidemia, aneurysms, cardiovascular metabolic diseases in Lebanon (LBTM in collaboration with Hotel Dieu de France (HDF) hospital), in the Middle East in the French p

روابط مفيدة

الجوائز والتميّزات

Golden Award 2022 de la Société Italienne d'athérosclérose