Ms. Laure CHAMY (EL)
Faculty of Medicine
Faculty of Science
Associate professor
(+961) 1 421 000 ext 3485 laure.chamy@usj.edu.lb
Laure El Chamy is an Associate Professor at the Faculty of Sciences- Saint-Joseph University of Beirut and the coordinator of the Master in « Functional Genomics and Proteomics ». She holds a PhD in “Molecular and Cellular Biology” from the University of Strasbourg. During her doctoral training at the laboratory of Insect models for Innate Immunity, she developed expertise in genetic analysis of innate immunity using the Drosophila melanogaster model. Her research interests focus on the characterization of host-pathogen interactions with a particular interest in the Bacillus cereus group. She is also involved in species identification through DNA barcoding as part of a strategy to monitor and preserve biodiversity. She has received several awards and distinctions, including the “L’Oréal- UNESCO for women in science”- international fellowship program 2013. In 2014, she was nominated to the “Women in science hall of fame program” of the US embassy in Beirut and the following year she was nominated to the « International Visitor Leadership Program- IVLP» to participate in the project « Women in Sciences Technology Engineering and Mathematics (STEM) fields ».
Highest degree : PhD in Molecular and Cellular Biology - Université de Strasbourg - France
+ Education
| Degrees | University | Country | Year |
|---|---|---|---|
| PHD Molecular and Cellular Biology | Université de Strasbourg | France | 2008 |
| DEA in Cellular and Molecular Biology | Université de Strasbourg | France | 2004 |
| Maitrise en Sciences de la vie et de la terre | Saint Joseph University of Beirut | Lebanon | 2003 |
+ Expertise field
Engineering and Technology, Sciences
+ Publications and communications
The NF-κB factor Relish is essential for the epithelial defenses protecting against δ-endotoxin dependent effects of Bacillus thuringiensis israelensis infection in the Drosophila model. Mouawad C, Kallassy Awad M, Liegeois S, Ferrandon D, Sanchis-Borja V and El Chamy L. Research in microbiology.2023
The PP4 phosphatase negatively regulates the IMD-NF-kB pathway during the Drosophila immune response.Salem Wehbeh L, Barakat D, Acker A, El Khoury R, Reichhart JM, Matt N and El Chamy L. J. Immunology. 2021
The fliK Gene Is Required for the Resistance of Bacillus thuringiensis to Antimicrobial Peptides and Virulence in Drosophila melanogaster. Attieh Z, Mouawad C, Rejasse A, Jehanno I, Perchat S, Hegna IK, Økstad OA, Kallassy Awad M, Sanchis-Borja V and El Chamy L. Frontiers in Microbiology. 2020 Dec 1
DltX of Bacillus
thuringiensis is essential for D-alanylation of teichoic acids and for
resistance to the humoral antimicrobial responses in insects.
Kamar R, Réjasse A, Jéhanno
I, Attieh Z, Courtin P, Chapot-Chartier MP, Nielsen-Leroux C, Lereclus D, El
Chamy L, Kallassy M and Sanchis-Borja V. Front Microbiol. 2017 Aug 3;8:1437
Advances in Myeloid-Like Cell Origins and Functions in the Model Organism Drosophila melanogaster. El Chamy L, Matt N and Reichhart JM. Microbiol Spectr. 2017. Jan; 5 (1).
The multilayered innate immune defense of the gut. El Chamy L, Matt N, Ntwasa M and Reichhart JM. Biomed J 2015; 38:276-284
Invertebrate Innate
Immune Defenses.
El Chamy L, Hetru C and Hoffmann JA. Chapter one of “The immune response to infection”, edited by Stefan H.E. Kaufmann, Barry T. Rouse and David L. Sacks. ASM press- Washington DC. Copyright 2011.
Sensing of danger
signals and pathogen-associated molecular patterns defines binary signaling
pathways upstream of Toll. El Chamy L, Leclerc V, Caldelari Iand Reichhart
JM. Nat Immunol. 2008 Oct ;9(10) :1165-1170.
Akirins, highly conserved nuclear proteins, required for NF-κB dependent gene expression in Drosophila and mice.Goto A, Matsushita K, Gesellchen V, El Chamy L, Kuttenkeuler D, Takeuchi O, Hoffmann JA, Akira S, Boutros M & Reichhart JM. Nat Immunol. 2008 Feb;9(2):216.