Dr. Karine ABOU KHALED
Faculty of Medicine
School of Midwifery
Associate professor
(+961) 1 421 000 ext 1604913 karine.aboukhaled@usj.edu.lb
Dr Karine Abou Khaled received her medical training at Saint Joseph University in Beirut before undertaking neurology residency at Drexel University (Philadelphia, USA) then clinical neurophysiology epilepsy fellowships at Columbia University, New York. She is an Associate Professor of Neurology at Saint Joseph University is currently practicing at Hotel-Dieu de France hospital in Beirut. Her main interests are clinical research in continuous EEG, sleep and epilepsy, status epilepticus and neuroimaging. She’s a fellow of the American Epilepsy Society, and co-founder and current president of Epsilon (medical and social association for Epilepsy in Lebanon).
+ Education
| Degrees | University | Country | Year |
|---|---|---|---|
| Epilepsie et neurophysiologie clinique | COLUMBIA UNIVERSITY | Etats-Unis | 2007 |
| Resident en neurologie | Drexel | Etats-Unis | 2005 |
| Docteur en Medecine | Saint Joseph University of Beirut | Lebanon | 1999 |
+ Teaching outside USJ
| Experience in University Teaching Outside USJ | Country | Institution | Start Date | End Date |
|---|---|---|---|---|
| teaching medical students on rounds, conferences, journal club | United States of America | COLUMBIA UNIVERSITY | 01/07/2005 | 30/06/2007 |
+ Expertise field
Medecine and Health
+ Research topics
Current projects : cEEG in critically patients in HDF : prospective study funded by USJ comparing simplified v/s standard cEEG. Establishing the registry of pregnancy antiepileptic drugs in Lebanon. fMRI for language in lebanese people with epilepsy. Effect of socioeconomic crisis on patients with multiple sclerosis epilepsy in Lebanon 2019 Direct impact of epilepsy training on school teachers in lebanon 2018-2020 Specificities of living with multiple sclerosis and quality of life across cultures, co-investigator and conceptor of a joint project with French MS research group, Grant from USJ and France 2017 Music effect on EEG in children with epilepsy, Mozart effect v/s Chawa effect 2016-2018 Study of effects of VNS on sleep and associated respiratory events in patients with epilepsy, Study funded by a research grant from Saint Joseph University. Lebanon. 2014-2017 Ictal PET utility in presurgical evaluation of epileptic patients- Risks of seizures in patients with abnormal renal function, and correlation to baseline EEG
+ Publications and communications
Articles: 1. Impact of the socioeconomic crisis in Lebanon on people with epilepsy. Samaha JN, Dagher JB, Abou Khaled KJ. Epilepsia Open. 2024 Oct 26. 2. Quantifying Vagus Nerve Stimulation Outcomes in Multifocal Refractory Epilepsy: A Model Across Multiple Surgeries. Zakar R, El Khoury JV, Prince G, Boutros M, Yaghi C, Matar M, Abou Khaled K, Moussa R.Cureus. 2024 Sep 1216(9). 3. Multinodular Vacuolating Posterior Fossa Lesion of Unknown Significance. Bou Issa, C. Abou Khaled, K. Choullamy, T. Rida, M. Nicolas-Jilwan, M. Case of the week, American Journal of Neuroradiology, accepted for publication, 2024. 4. Costa J, Macaron G, Abou Khaled KJ. Biomarkers in multiple sclerosis: an SAFE_USJ_update. Biomarkers in Neuropsychiatry. Volume 9, 2023. 5. Matta Christian, Hamze Rouba, Abi Nahed Rachelle, Azar Hiba, Abou Khaled Karine J. Abnormal inpatient EEG predicts seizure occurrence independently of renal function. Epilepsy Behav Rep, 2023 Aug 523:100615. 6. El-Hayeck R, Wehbé A, Baddoura R, Khoury R, Bassil N, Abou Khaled K, Koussa S, Richa S, Alameddine A, Sellal F. Letter Category Fluency: Normative Data for Lebanese Older Adults. J Alzheimers Dis. 2023 Mar 25. doi: 10.3233/JAD-221121. 7. Abou Khaled KJ, Bou Nasif Mei, Freiji C, Hirsch LJ, Fong MWK. Rapid Response EEG with Needle Electrodes in an Intensive Care Unit with Limited Resources. Clin Neurophysiol Pract. 2023 Feb 21;8 :44-48. 8. El-Hayeck R, Baddoura R, Wehbé A, Bassil N, Koussa S, Abou Khaled K, Richa S, Khoury R, Alameddine A, Sellal F. An adapted Arabic version of the Test of Nine Images for the illiterate Lebanese population: Validation and preliminary normative data. J Int Neuropsychol Soc. 2023 Mar; 29(3):316-323. 9. Abou Khaled K, Bakhos G. Instagram as a learning tool in neurology : a prospective study. JML 2022. 10. El-Hayeck R, Baddoura B, Wehbé A, Bassil N, Koussa K, Abou Khaled K, Richa S, Khoury R, Alameddine A, Sellal F. An adapted version of the Test of Nine Images for the illiterate Lebanese population: validation and preliminary normative data. JINS. 2022 ; May 4 :1-8. 11. M. Ibrahim, A. Henry, K. Abou Khaled, C. Bensa, T. Moreau, M. Montreuil, A. Tourbah, The French Lebanese MS study group. Health related quality of life and perceived social support in French and Lebanese MS patients : a comparative study. MSRD 2022 ; 61. 12. Abou Khaled K, Azar C, Haidar M. Ictal and interictal FDG-PET in anti-NMDAR encephalitis with mutism, Radiology Case reports. 2021 ; 16 (12) : 3892-3897 13. Abi Nahed R, Succarieh G, Soueidy AA, Baz P, Macaron G, Abou Khaled KJ. MOG-related bilateral optic neuritis in a patient with cystic fibrosis. J Clin Images Med Case Rep. 2021; 2(3): 1198 14. Abou Khaled KJ, Ibrahim M. I, Moussa RF. Impact of epilepsy training on school teachers and counselors: an intervention study in Lebanon. Epilepsy Behav Rep, 2020(14). 15. El-Hayeck R, Baddoura R, Wehbé A, Bassil N, Koussa S, Abou Khaled K, Richa S, Khoury R, Alameddine A, Sellal F. An Arabic version of the Mini-Mental State Examination for the Lebanese population. J Alzheimers Dis. 2019 Aug 12;-1(1):525-540. 16. Abou Khaled K, Khoury J, Macaron G, Richa S. Forced normalization and psychosis induced by lacosamide. Seizure 2016; 41: 96-99. 17. Akman CI, Abou Khaled KJ, Segal E, Micic V, Riviello JJ. Generalized periodic epileptiform discharges in critically ill children: Clinical features, and outcome. Epilepsy Res 2013 Oct;106(3):378-385. 18. Foreman B, Claassen J, Abou Khaled K,Jirsch J, Alschuler DM, Wittman J, Emerson RG, Hirsch LJ. Generalized Periodic Discharges in the Critically Ill: A Matched Case Control Study of 200 Patients. Neurology 2012. Nov 6; 79(19) :1951-60 19. Hirsch LJ, Pang T, Claassen J, Chang C, Abou Khaled K, Wittman J, Emerson RG: Focal seizures induced by alerting stimuli in critically ill patients. Epilepsia 2008 Jun; 49(6):968-73). 20. Abou Khaled KJ, Hirsch LJ. Updates in the management of seizures and status epilepticus in critically ill patients. Neurol Clin. 2008 May; 26(2):385-408. 21. Abou Khaled K, Hirsch LJ: Advances in the management of seizures and status epilepticus in critically Ill patients. Critical Care Clin 2006; 22(4): 637-659. 22. Kumar MA, Urrutia VC, Thomas CE, Abou-Khaled KJ, Schwartzman RJ: The syndrome of irreversible acidosis after prolonged propofol infusion. Neurocrit Care 2005; 3(3):257-9 23. Assaf BA, Mohamed FB, Abou-Khaled KJ, Williams MJ, Yazeji MS, Haselgrove J, and Faro SH. Diffusion Tensor Imaging of the Hippocampal Formation in Temporal Lobe Epilepsy AJNR 2003; 24: 1857 – 1862 24. Abou Khaled K, Koussa S, Chemaly R: Vertige isolé révélant un accident vasculaire cérébral: Bulletin de l’Université Saint Joseph, Faculté de Médecine, 1999. Book chapter : 1. Abou Khaled K, Hirsch LJ: Treatment of the hospitalized patient with new onset seizures. In J. French/ N. Delanty Ed. Therapeutic strategies in epilepsy, 2009. 2. Ibrahim M, Henry A, Abou Khaled K, Bensa C, Deschamps R, Gout O, Montreuil M, Tourbah A: “SEP, annonce du diagnostic et soutien social à travers les cultures, étude franco-libanaise ». La sclérose en plaques. La maladie. Le quotidien, Presses universitaires François-Rabelais, 2020.
+ Awards and recognition
• Fellow of the American Epilepsy Society