En | Ar

Dr Carla IRANI NASR

Faculté de médecine
Faculté de pharmacie

Professeur associé

(+961) 1 421 000 ext carla.irani@usj.edu.lb

Dr Irani obtained her Medicine Doctor Diploma from St Joseph University in Beyrouth. She did Internal Medicine residency Cooper Hospital, USA the Allergy and Clinical Immunology fellowship a the Hospital University of Pennsylvania, USA . She is an American Board diplomate of Internal Medicine and Allergy/Immunology. Master of Clinical Epidemiology: AUB, 2017 Associate Professor of Medicine St Joseph University, Beirut since December 2018 and teaches Allergy/Immunology and Autoimmunity at St Joseph University She is the Head of Department of Internal Medicine & Clincial Immunology at Hotel Dieu De France Beyrouth, Lebanon. She was interested in many researches and had a lot of publications in the Journal of Allergy and Clinical Immunology and other journals. Fellow of The American Academy of Allergy, Asthma and Immunology and President of the Lebanese Society of Allergy and Immunology, she gained several local and American Awards. She participated in many clinical trials in Allergy & Immunology. She treats all Allergic diseases such as Urticaria, Allergic Rhinitis, Asthma, Atopic Dermatitis, Food Allergies as well as Primary immunodeficiencies among others.


DiplômeUniversitéPaysAnnée
Master of Science Clinical EpidemiologyAmerican University of Beirut (AUB)Liban2017
American Board of Allergy & ImmunologyUniversity of PennsylvaniaEtats-Unis2001
American Board of Internal MedicineRutgers University UMDNJEtats-Unis1999
Doctor of MedicineUniversité Saint-Joseph de BeyrouthLiban1995

Faculte de Medecine

Expérience professionnelleOrganisationDate débutDate fin
Part -time Faculty ;Attending Physician Allergy & Clinical ImmunologyHospital University of Alberta09/09/201009/07/2018
Medecin (Chef de service Medecine Interne & Immunologie Clinique depuis 2022 jusque cette dateHotel Dieu de France09/09/200409/11/2024

Médecine et Santé

1. C. Irani & G.Halaby. Hypogonadotropic Hypogonadism: Evolution Prognosis of 47 patients. 1995 2. C. Irani & A. Reginato. Cardiac Manifestations of Sarcoidosis.American College of Rheumatology 1998 3. C. Irani , A. Reboli et al. PCR-Mediated Ribotyping of Pseudomonas Cepacia Presented at the American Society of Microbiology in Atlanta. 1998 4. C. Irani, A.J. Ammit et al. CRE but not AP-1, NF-kB, or C/EBP, mediates camp-induced IL-6 gene expression in human airway smooth muscle cells. Abstract presented at the American Thoracic Society in San Francisco. May 2001 5. C. Irani, N. Gordon, B. Zweiman & A.I. Levinson. Chronic Urticaria/Angioedema and Graves’ Disease: Coexistence of two Anti-Receptor Antibody Mediated diseases. Journal of Allergy and Clinical Immunology 2001 Nov108(5)874 6. C. Irani, N. Gordon & A.I. Levinson. A novel approach to cardiac bypass surgery in a patient with cold-induced urticaria. . Journal of Allergy and Clinical Immunology 2002, January Vol.109 (1) S128 7. C. Irani & A. Apter. Evaluation of Eosinophilia. Published in Patterson’s Allergic Diseases textbook: 6th edition, 2002 Lippincott Williams & Wilkins. 8. A. Ammit, A. Lazar, C. Irani et al. TNFalpha-induced secretion of RANTES and IL-6 from HASM cells: Modulation by Glucocorticoids and alpha-agonists. American Journal of Respiratory and Cellular Molecular Biology. 2002 Apr;26(4):465-74 9. C. Irani, E. Goncharova, D. Hunter, C. Walker, R. Panettieri & V. krymskaya. PI3K but not tuberin is required for PDGF-induced cell migration. American Journal of Physiology; Lung Cellular Molecular Physiology. 2002 Apr;282(4):L854-62 10. E. Goncharova, A. Ammit, C. Irani et al. PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. American Journal of Physiology; Lung Cellular Molecular Physiology. 2002 Aug;283(2):L354-63 11. E. Goncharova, C. Billington, C. Irani et al. Cyclic-AMP-Mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. American Journal of Respiratory and Cellular Molecular Biology. 2003 Jul;29(1):19-27. Epub 2003 Jan 31 12. C. Irani, S. Cowper,G. Aftimos, A Barbari. Nephrogenic Fibrosing Dermopathy: a unique fibrosing skin condition of renal insufficiency associated with CD34/procollagen dual positive circulating fibrocytes. . Journal of Allergy and Clinical Immunology 2004 Feb. 113(2) S294 13. C. Irani, M. Germanos, H. Kazma, V. Merhej. Food Allergy in Lebanon: Is Sesame the “Middle Easter” Peanut. . Journal of Allergy and Clinical Immunology 2006 Feb117 S37 14. C. Irani, N. D. Gordon, A. I. Levinson Normothermic cardioplegia in a patient with cold-induced urticaria. . Journal of Allergy and Clinical Immunology 2007 September 120(3), 722-723 15. C. Irani, G. Maalouly, R. El Nemnoum. Stevens – Johnson syndrome : a retrospective study in Hotel Dieu de France Hospital Beirut, Lebanon. Journal of Allergy and Clinical Immunology 2008 February 121(2) S193. 16. C. Irani, F. Haddad, G. Maalouly, R. El Nemnoum. Curcumin in Stevens-Johnsons Syndrome: Culprit or bystander? WAO Journal , April 2009 17. C. Irani, H. Hajj, G. Halaby. Chronic Urticaria and Autoimmune Thyroid Disease in Lebanon. Journal of Allergy and Clinical Immunology 2009 February Vol. 123, Issue 2, Supplement, Page S105 18. Z. E. Baz, M. Nader, F. Zaitoun, R. Dana, C. Irani, A. Hejjaoui, E. Kairallah, B. Abi Salloum, S. Abi Dib Antoun, S. Chreiteh,H. Maatouk, B. Andary. Analysis of Airborne Pollen in Lebanon. Journal of Allergy and Clinical Immunology.2010 Feb.125,(2)S1;AB15 19. Airborne pollen sampling and the correlation with allergic asthma and rhinoconjunctivitis in LEBANON.C. Irani, M. Karam, F.Zeitoun, Z.Baz, H.Maatouk, R. Dana. Allergy 2010.June.65S92 20. C. Irani, G. Maalouly, M. Germanos, H. Kazma, Food Allergy in Lebanon: Is Sesame Seed the “Middle Eastern” Peanut.WAO Journal 2011; 4:000 21. C. Irani,R. Abi Saleh, M.Jammal, F.Haddad.Efficacy Of High-dose Sublingual Immunotherapy In Patients Allergic To Pollen In Real-life Clinical Practice. J Allergy Clin. Immunology Feb 2011. 22. C. Irani, M. Jammal, G. Asmar, H. Hajj, G. Halaby . Chronic Urticaria and auto-immune thyroditis. Lebanese Medical Journal vol. 60, no.2, 2012 23. C. Irani, C. Saade, C. Dagher. Allergy to General Anesthetics: Evaluation of Patients Profile ; Hotel Dieu de France hospital,Beirut, LEBANON. J ALLERGY CLIN IMMUNOL .FEBRUARY 2012 24. Eosinophilic Esophagitis and Pollinosis. Carla Irani, MD FAAAAI. Course 1610 Upper Airway Disease and Comorbidities; Lecture presented at the Annual Meeting of the American Academy of Allergy and Clinical Immunology 2012 25. C. Irani, M. Karam, Z. Baz, H. Maatouk, F. Zaitoun. Airborne pollen concentrations and the incidence of allergic asthma and rhinoconjunctivitis in Lebanon. Revue Française dAllergologie.Volume 53, Issue 5, September 2013, Pages 441–445 26. Carla Irani, MD, FAAAAI1,2, Maya Mouzannar1.The Hygiene Hypothesis : Aeroallergen Sensitization in Allergic Rhinitis Patients Living in Rural and Urban Areas of Lebanon. J Allergy Clin Immunol Feb 2013. 27. C.Irani, J.Saliba.Effect of Passive Smoking on Athma Severity in Children. European Academy of Allergy and Immunology 2013 28. T.Bazarbachi,Y.Haddad,C.Irani et al. Choosing the best panel of aeroallergens prick tests for patients in Lebanon with allergic rhinitis and asthma: A retrospective study of 2350 patients. Rev Mal Respir. 2014 Nov;31(9):839-48. doi: 10.1016/j.rmr.2014.01.010. Epub 2014 Feb 22 29. Carla Irani, MD1,2, Roula Abi Saleh, MD1, Mouin Jammal, MD1 and Fady HaddadM.D. High-dose sublingual immunotherapy in patients with uncontrolled allergic rhinitis sensitized to pollen: a real-life clinical study
 Int Forum Allergy Rhinol. 2014 Oct;4(10):802-7 30. C. Irani, C. Saade, C. Dagher and P.Yazbeck Allergy to General Anesthetics: Evaluation of Patients Profile.International Journal of Anesthetics and Anesthesiology.2014 Oct Vol1,Issue 3 31. C. Irani, S. Abou Nakad, O.Nahas. Omalizumab: A case series in asthma and other clinical applications. Revue Française d'Allergologie. Vol 54 - N°3 - April 2014 p. 87-286 32. C.Irani, O.Nahas, Ch Sabbagh, A. Zoghbi, F Haddad.Outcomes of emergency room visits for asthma. Abstract presented at the European Academy of Allergy and immunology EAACI 2015. 33. R.Azzam, J.Boutros, C.Irani. Hereditary Angioedema : a literature review and a national management guidelines. J Med Liban. 2015 Apr-Jun;63(2):97-101 34. C. Irani, G. Maalouly. Prevalence of Self-Reported Food Allergy in Lebanon: A Middle-Eastern Taste. International Scholarly Research Notices (ISRN) Volume 2015, Article ID 639796, 5 pages 35. C. Irani, O.Nahas. Real-life Experience of Clinical Efficacy of Omalizumab use in the Middle-East: Should we also be Concerned about Parasites? Clinical-anti-inflammatory-and-anti-allergy-drugs Volume 2, 2015. 36. C. Irani, M. Boustany, G. Maalouly, J. Choucair. Immunomodulators use unmasking immunodeficiency in 3 patients with low IgA: Misdiagnosis or Complication? J Allergy Clin Immunol. Feb 2015, 135(2) 37. C. Irani, C. Habre. Validation of the Urticaria Control Test in Arabic:Evaluation of disease control in chronic urticarial:a real-life study using UCT. Oral presentation. Allergy 2015 38. Carla Irani, S Fattah,J Saliba. Real-life study assessing the clinical diagnosis of allergy and sensitization in atopic patients using the ISAC method (molecular allergology) . J Allergy Clin Immunol. February 2017 : 139(2) AB337 39. C. Irani, N. Arej Evaluation of allergic sensitization by specific IgE or prick skin tests in patients with allergic conjonctivitis . Int J Ophtalmology 2017, August 22 40. Irani C, Hallit S, Weller K, Maurer M, El Habre C, Salameh P. Chronic urticaria in most patients is poorly controlled. Results of the development, validation, and real life application of the arabic urticaria control test. Saudi Med Journal. 2017 Dec;38(12):1230-1236 41. C. Irani, M.Kassab. Impact of Pollution on the Quality of Life of Lebanese Allergic Rhinitis patients: a cross- sectional study. J Allergy Clin Immunology February 2018: 141(2) AB128 42. C. Irani, E.Kozaily. Association between serum leptin and control of asthma in adult Lebanese atopic asthmatics: a real-life study.(E.Poster).EAACI Munich 2018, J Allergy , May 2018 43. C Hanna, D Villa, C. Irani, M.Ghosn, E. El Rassy Leukocytoclastic vasculitis and desensitization to high-dose methotrexate in primary central nervous system lymphoma. Clinical Lymphoma, Myeloma & Leukemia. March 2018 44. A. Daher, G. Maalouf, C. Irani. When intravenous immunoglobulins improve a chronic diarrhea . Revue de Medecine Interne March 2018 45. Irani C, Adib S, Halaby G, Sibai A. Obesity/overweight and asthma control in LEBANESE adults: a cross-sectional study.BMC Public Health 2019 Jun 17;19(1):769 46. Irani C, Hallit S, Mouzannar M, Salameh P. Aeroallergen sensitization and upper respiratory allergies among patients living in rural and urban areas: Real-life exploration of the hygiene hypothesis. WAO J 2019, sept 30;12(9) 47. Lee PY, Kellner ES, Huang Y et al. Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). J Allergy Clin Immunol. 2020 Jan 13. pii: S0091-6749(20)30030 48. Maalouly G, Hajal J, Saliba Y et al. Beneficial role of simvastatin in experimental autoimmune myositis. Int Immunopharmacol. 2019 Dec 18;79:106051 49. Carla Irani, Souheil Hallit, Stephanie Daccache, Pascale Salameh The use of Omalizumab in Severe Allergic asthma and Chronic Spontaneous Urticaria: real-life experience Journal of Allergy and Clinical Immunology,Feb 2020; Vol. 145, Issue 2, AB34 50. Tawil G, Tawil P, Irani C. Zirconium Implant as an Alternative to Titanium Implant in a Case of Type IV Titanium Allergy: Case Report. Int J Oral Maxillofac Implants. 2020 May/Jun;35(3):639-644 51. Klimek L, Jutel M, Akdis C, Bousquet J, Akdis M, Bachert C, Agache I, Ansotegui I, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Chivato T, Cruz AA, Czarlewski W, Giacco SD, Du H, Fonseca JA, Gao Y, Haahtela T, Hoffmann-Sommergruber K, Ivancevich JC, Khaltaev N, Knol EF, Kuna P, Larenas-Linnemann D, Melen E, Mullol J, Naclerio R, Ohta K, Okamoto Y, O'Mahony L, Onorato GL, Papadopoulos NG, Pawankar R, Pfaar O, Samolinski B, Schwarze J, Toppila-Salmi S, Shamji MH, Ventura MT, Valiulis A, Yorgancioglu A, Matricardi P, Zuberbier T; ARIA-MASK study group( corporate author). Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI statement. Allergy. 2020 Apr 24. 52. Bousquet J, Akdis C, Jutel M, Bachert C, Klimek L, Agache I, Ansotegui IJ, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Chivato T, Cruz AA, Czarlewski W, Del Giacco S, Du H, Fonseca JA, Gao Y, Haahtela T, Hoffmann-Sommergruber K, Ivancevich JC, Khaltaev N, Knol EF, Kuna P, Larenas-Linnemann D, Mullol J, Naclerio R, Ohta K, Okamoto Y, O'Mahony L, Onorato GL, Papadopoulos NG, Pfaar O, Samolinski B, Schwarze J, Toppila-Salmi S, Teresa Ventura M, Valiulis A, Yorgancioglu A, Zuberbier T; ARIA-MASK study group(corporate author). Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement. Allergy. 2020 Mar 31 53. Carla Irani, Souheil Hallit, Marilyn Karam, Candie Jammal, Martine Kai, Pascale Salameh. Overview of atopic dermatitis in a Lebanese population: A cross-sectional study. EAACI 2020 54. Samah Tawil, Carla Irani, Riwa Kfoury et al. The Arabic Urticaria Activity Score and Chronic Urticaria Quality of Life Questionnaire: validation and correlations. Int J Dermatol. 2020, Aug;59(8):893-901 55. Incorvaia C, Al-Ahmad M, Ansotegui I, et al. Personalized Medicine for allergy treatment: allergen immunotherapy still a unique and unmatched model [published online ahead of print, 2020 Sep 1]. Allergy. 56. Rouadi PW, Idriss SA, Naclerio RM et al. Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD). World Allergy Organ. Journal 2020 Oct;13(10) 57. Carla Irani, Angela Hacksu. Grains of Wisdom: Transgenic Rice for Oral Allergen Immunotherapy in Japanese Cedar Pollen-Allergic Patients. Int Arch Allergy Immunol.2020, Dec 15, 1-3 58. Bousquet J, Agache I, Blain H, Jutel M,et al Management of anaphylaxis due to COVID-19 vaccines in the elderly. Allergy. 2021 Apr 2. doi: 10.1111/all.14838. Epub ahead of print. PMID: 33811358. 59. Tawil S, Irani C, Kfoury R, Abramian S, Salameh P, Weller K, Maurer M, Ezzedine K. Assessment of urticaria using a self-reported diagnosis tool (SRUD): a multicenter validation study. J Eur Acad Dermatol Venereol. 2021 Apr 60. Aghamohammadi A, Rezaei N, Yazdani R, Delavari S, Kutukculer N, Topyildiz E, Ozen A, Baris S, Karakoc-Aydiner E, Kilic SS, Kose H, Gulez N, Genel F, Reisli I, Djenouhat K, Tahiat A, Boukari R, Ladj S, Belbouab R, Ferhani Y, Belaid B, Djidjik R, Kechout N, Attal N, Saidani K, Barbouche R, Bousfiha A, Sobh A, Rizk R, Elnagdy MH, Al-Ahmed M, Al-Tamemi S, Nasrullayeva G, Adeli M, Al-Nesf M, Hassen A, Mehawej C, Irani C, Megarbane A, Quinn J; MENA-I. E. I. Study Group, Maródi L, Modell V, Modell F, Al-Herz W, Geha RS, Abolhassani H. Consensus Middle East and North Africa Registry on Inborn Errors of Immunity. J Clin Immunol. 2021 May 29. 61. Tawil S, Irani C, Kfoury R, Abramian S, Salameh P, Weller K, Maurer M, Ezzedine K. Assessment of urticaria using a self-reported diagnosis tool (SRUD): a multicentre validation study. J Eur Acad Dermatol Venereol. 2021 Oct;35(10) 62. Sakakini J, Irani C, Bikai R, Sahyoun G, Hallit S, Salameh P, Dano D. Prevalence of Food Allergy among Schoolchildren in Lebanon. Int Arch Allergy Immunol. 2022 63. El-Sayed ZA, El-Ghoneimy DH, Ortega-Martell JA, Radwan N, Aldave JC, Al-Herz W, Al-Nesf MA, Condino-Neto A, Cole T, Eley B, Erwa NHH, Espinosa-Padilla S, Faria E, Rosario Filho NA, Fuleihan R, Galal N, Garabedian E, Hintermeyer M, Imai K, Irani C, Kamal E, Kechout N, Klocperk A, Levin M, Milota T, Ouederni M, Paganelli R, Pignata C, Qamar FN, Quinti I, Qureshi S, Radhakrishnan N, Rezaei N, Routes J, Singh S, Siniah S, Abdel-Hakam Taha I, Tanno LK, Van Dort B, Volokha A, Sullivan K. Allergic manifestations of inborn errors of immunity and their impact on the diagnosis: A worldwide study. World Allergy Organ J. 2022 Jun 17;15(6):100657 64. Tawil S, Irani C, Kfoury R, Abramian S, Salameh P, Weller K, Maurer M, Ezzedine K. Association of Chronic Urticaria with Psychological Distress: A Multicentre Cross-sectional Study. Acta Derm Venereol. 2023 Feb 14;103 65. Wajdi Abi Saleh1 , Zuhair Alameh2 , Zeina Aoun Bacha3* , Joudy Bahous4 , Pierre Bou Khalil5 , Zahia Chahine7 , Hassan Chami5,6, Georges Dabar3 , Hassan Dheiny8 , Alfred Dib9 , Dany farhat10, Carla Irani11, Georges Juvelekian4 , Nadim Kanj5 , Bassam Mansour12, Moussa Riachi3 , Mirna Waked4 , Mohamad Yassine10, Carole Youakim13, Salah Zeinedine5 and Fares . PRevalence of the Eosinophilic Phenotype Among SeveRE asthma patients in Lebanon: results of the PREPARE study. Allergy Asthma Clin Immunol 19, 80 (2023) 66. Dagher J, Antonios D, Chollet-Martin S, de Chaisemartin L, Pallardy M, Azouri H, Irani C. Drug-induced hypersensitivity reactions in a Lebanese outpatient population: A decade-long retrospective analysis (2012-2021). J Allergy Clin Immunol Glob. 2023 Sep 17;3(1):10016 67. Maurer M, Abuzakouk M, Al-Ahmad M, Al-Herz W, Alrayes H, Al-Tamemi S, Arnaout R, Binghadeer H, Gutta R, Irani C, Mobayed H, Nasr I, Shendi H, Zaitoun F. Consensus on diagnosis and management of Hereditary Angioedema in the Middle East: A Delphi initiative. World Allergy Organ J. 2022 Dec 24;16(1):100729. 68. Maurer M, Ensina LF, Gimenez-Arnau AM, Sussman G, Hide M, Saini S, Grattan C, Fomina D, Rigopoulos D, Berard F, Canonica GW, Rockmann H, Irani C, Szepietowski JC, Leflein J, Bernstein JA, Peter JG, Kulthanan K, Godse K, Ardusso L, Ukhanova O, Staubach P, Sinclair R, Gogate S, Thomsen SF, Tanus T, Ye YM, Burciu A, Barve A, Modi D, Scosyrev E, Hua E, Letzelter K, Varanasi V, Patekar M, Severin T; PEARL-1 and PEARL-2 trial investigators. Efficacy and safety of ligelizumab in adults and adolescents with chronic spontaneous urticaria: results of two phase 3 randomised controlled trials. Lancet. 2023 Nov 23:S0140-6736(23)01684-7. 69. Turner PJ, Ansotegui IJ, Campbell DE, Cardona V, Carr S, Custovic A, Durham S, Ebisawa M, Geller M, Gonzalez-Estrada A, Greenberger PA, Hossny E, Irani C, Leung ASY, Levin ME, Muraro A, Oppenheimer JJ, Ortega Martell JA, Pouessel G, Rial MJ, Senna G, Tanno LK, Wallace DV, Worm M, Morais-Almeida M; WAO Anaphylaxis Committee and WAO Allergen Immunotherapy Committee. Updated grading system for systemic allergic reactions: Joint Statement of the World Allergy Organization Anaphylaxis Committee and Allergen Immunotherapy Committee. World Allergy Organ J. 2024 Feb 10;17(3):100876. 70. https://www.pathlms.com/wao/courses/1890: urticaria modules 71. Managing of Asthma with with Allergic rhinitis in Adults 2016 http://www.worldallergy.org/modules/course/view.php?id17

1. C. Irani & G.Halaby. Hypogonadotropic Hypogonadism: Evolution Prognosis of 47 patients. 1995 2. C. Irani & A. Reginato. Cardiac Manifestations of Sarcoidosis.American College of Rheumatology 1998 3. C. Irani , A. Reboli et al. PCR-Mediated Ribotyping of Pseudomonas Cepacia Presented at the American Society of Microbiology in Atlanta. 1998 4. C. Irani, A.J. Ammit et al. CRE but not AP-1, NF-kB, or C/EBP, mediates camp-induced IL-6 gene expression in human airway smooth muscle cells. Abstract presented at the American Thoracic Society in San Francisco. May 2001 5. C. Irani, N. Gordon, B. Zweiman & A.I. Levinson. Chronic Urticaria/Angioedema and Graves’ Disease: Coexistence of two Anti-Receptor Antibody Mediated diseases. Journal of Allergy and Clinical Immunology 2001 Nov108(5)874 6. C. Irani, N. Gordon & A.I. Levinson. A novel approach to cardiac bypass surgery in a patient with cold-induced urticaria. . Journal of Allergy and Clinical Immunology 2002, January Vol.109 (1) S128 7. C. Irani & A. Apter. Evaluation of Eosinophilia. Published in Patterson’s Allergic Diseases textbook: 6th edition, 2002 Lippincott Williams & Wilkins. 8. A. Ammit, A. Lazar, C. Irani et al. TNFalpha-induced secretion of RANTES and IL-6 from HASM cells: Modulation by Glucocorticoids and alpha-agonists. American Journal of Respiratory and Cellular Molecular Biology. 2002 Apr;26(4):465-74 9. C. Irani, E. Goncharova, D. Hunter, C. Walker, R. Panettieri & V. krymskaya. PI3K but not tuberin is required for PDGF-induced cell migration. American Journal of Physiology; Lung Cellular Molecular Physiology. 2002 Apr;282(4):L854-62 10. E. Goncharova, A. Ammit, C. Irani et al. PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. American Journal of Physiology; Lung Cellular Molecular Physiology. 2002 Aug;283(2):L354-63 11. E. Goncharova, C. Billington, C. Irani et al. Cyclic-AMP-Mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. American Journal of Respiratory and Cellular Molecular Biology. 2003 Jul;29(1):19-27. Epub 2003 Jan 31 12. C. Irani, S. Cowper,G. Aftimos, A Barbari. Nephrogenic Fibrosing Dermopathy: a unique fibrosing skin condition of renal insufficiency associated with CD34/procollagen dual positive circulating fibrocytes. . Journal of Allergy and Clinical Immunology 2004 Feb. 113(2) S294 13. C. Irani, M. Germanos, H. Kazma, V. Merhej. Food Allergy in Lebanon: Is Sesame the “Middle Easter” Peanut. . Journal of Allergy and Clinical Immunology 2006 Feb117 S37 14. C. Irani, N. D. Gordon, A. I. Levinson Normothermic cardioplegia in a patient with cold-induced urticaria. . Journal of Allergy and Clinical Immunology 2007 September 120(3), 722-723 15. C. Irani, G. Maalouly, R. El Nemnoum. Stevens – Johnson syndrome : a retrospective study in Hotel Dieu de France Hospital Beirut, Lebanon. Journal of Allergy and Clinical Immunology 2008 February 121(2) S193. 16. C. Irani, F. Haddad, G. Maalouly, R. El Nemnoum. Curcumin in Stevens-Johnsons Syndrome: Culprit or bystander? WAO Journal , April 2009 17. C. Irani, H. Hajj, G. Halaby. Chronic Urticaria and Autoimmune Thyroid Disease in Lebanon. Journal of Allergy and Clinical Immunology 2009 February Vol. 123, Issue 2, Supplement, Page S105 18. Z. E. Baz, M. Nader, F. Zaitoun, R. Dana, C. Irani, A. Hejjaoui, E. Kairallah, B. Abi Salloum, S. Abi Dib Antoun, S. Chreiteh,H. Maatouk, B. Andary. Analysis of Airborne Pollen in Lebanon. Journal of Allergy and Clinical Immunology.2010 Feb.125,(2)S1;AB15 19. Airborne pollen sampling and the correlation with allergic asthma and rhinoconjunctivitis in LEBANON.C. Irani, M. Karam, F.Zeitoun, Z.Baz, H.Maatouk, R. Dana. Allergy 2010.June.65S92 20. C. Irani, G. Maalouly, M. Germanos, H. Kazma, Food Allergy in Lebanon: Is Sesame Seed the “Middle Eastern” Peanut.WAO Journal 2011; 4:000 21. C. Irani,R. Abi Saleh, M.Jammal, F.Haddad.Efficacy Of High-dose Sublingual Immunotherapy In Patients Allergic To Pollen In Real-life Clinical Practice. J Allergy Clin. Immunology Feb 2011. 22. C. Irani, M. Jammal, G. Asmar, H. Hajj, G. Halaby . Chronic Urticaria and auto-immune thyroditis. Lebanese Medical Journal vol. 60, no.2, 2012 23. C. Irani, C. Saade, C. Dagher. Allergy to General Anesthetics: Evaluation of Patients Profile ; Hotel Dieu de France hospital,Beirut, LEBANON. J ALLERGY CLIN IMMUNOL .FEBRUARY 2012 24. Eosinophilic Esophagitis and Pollinosis. Carla Irani, MD FAAAAI. Course 1610 Upper Airway Disease and Comorbidities; Lecture presented at the Annual Meeting of the American Academy of Allergy and Clinical Immunology 2012 25. C. Irani, M. Karam, Z. Baz, H. Maatouk, F. Zaitoun. Airborne pollen concentrations and the incidence of allergic asthma and rhinoconjunctivitis in Lebanon. Revue Française dAllergologie.Volume 53, Issue 5, September 2013, Pages 441–445 26. Carla Irani, MD, FAAAAI1,2, Maya Mouzannar1.The Hygiene Hypothesis : Aeroallergen Sensitization in Allergic Rhinitis Patients Living in Rural and Urban Areas of Lebanon. J Allergy Clin Immunol Feb 2013. 27. C.Irani, J.Saliba.Effect of Passive Smoking on Athma Severity in Children. European Academy of Allergy and Immunology 2013 28. T.Bazarbachi,Y.Haddad,C.Irani et al. Choosing the best panel of aeroallergens prick tests for patients in Lebanon with allergic rhinitis and asthma: A retrospective study of 2350 patients. Rev Mal Respir. 2014 Nov;31(9):839-48. doi: 10.1016/j.rmr.2014.01.010. Epub 2014 Feb 22 29. Carla Irani, MD1,2, Roula Abi Saleh, MD1, Mouin Jammal, MD1 and Fady HaddadM.D. High-dose sublingual immunotherapy in patients with uncontrolled allergic rhinitis sensitized to pollen: a real-life clinical study
 Int Forum Allergy Rhinol. 2014 Oct;4(10):802-7 30. C. Irani, C. Saade, C. Dagher and P.Yazbeck Allergy to General Anesthetics: Evaluation of Patients Profile.International Journal of Anesthetics and Anesthesiology.2014 Oct Vol1,Issue 3 31. C. Irani, S. Abou Nakad, O.Nahas. Omalizumab: A case series in asthma and other clinical applications. Revue Française d'Allergologie. Vol 54 - N°3 - April 2014 p. 87-286 32. C.Irani, O.Nahas, Ch Sabbagh, A. Zoghbi, F Haddad.Outcomes of emergency room visits for asthma. Abstract presented at the European Academy of Allergy and immunology EAACI 2015. 33. R.Azzam, J.Boutros, C.Irani. Hereditary Angioedema : a literature review and a national management guidelines. J Med Liban. 2015 Apr-Jun;63(2):97-101 34. C. Irani, G. Maalouly. Prevalence of Self-Reported Food Allergy in Lebanon: A Middle-Eastern Taste. International Scholarly Research Notices (ISRN) Volume 2015, Article ID 639796, 5 pages 35. C. Irani, O.Nahas. Real-life Experience of Clinical Efficacy of Omalizumab use in the Middle-East: Should we also be Concerned about Parasites? Clinical-anti-inflammatory-and-anti-allergy-drugs Volume 2, 2015. 36. C. Irani, M. Boustany, G. Maalouly, J. Choucair. Immunomodulators use unmasking immunodeficiency in 3 patients with low IgA: Misdiagnosis or Complication? J Allergy Clin Immunol. Feb 2015, 135(2) 37. C. Irani, C. Habre. Validation of the Urticaria Control Test in Arabic:Evaluation of disease control in chronic urticarial:a real-life study using UCT. Oral presentation. Allergy 2015 38. Carla Irani, S Fattah,J Saliba. Real-life study assessing the clinical diagnosis of allergy and sensitization in atopic patients using the ISAC method (molecular allergology) . J Allergy Clin Immunol. February 2017 : 139(2) AB337 39. C. Irani, N. Arej Evaluation of allergic sensitization by specific IgE or prick skin tests in patients with allergic conjonctivitis . Int J Ophtalmology 2017, August 22 40. Irani C, Hallit S, Weller K, Maurer M, El Habre C, Salameh P. Chronic urticaria in most patients is poorly controlled. Results of the development, validation, and real life application of the arabic urticaria control test. Saudi Med Journal. 2017 Dec;38(12):1230-1236 41. C. Irani, M.Kassab. Impact of Pollution on the Quality of Life of Lebanese Allergic Rhinitis patients: a cross- sectional study. J Allergy Clin Immunology February 2018: 141(2) AB128 42. C. Irani, E.Kozaily. Association between serum leptin and control of asthma in adult Lebanese atopic asthmatics: a real-life study.(E.Poster).EAACI Munich 2018, J Allergy , May 2018 43. C Hanna, D Villa, C. Irani, M.Ghosn, E. El Rassy Leukocytoclastic vasculitis and desensitization to high-dose methotrexate in primary central nervous system lymphoma. Clinical Lymphoma, Myeloma & Leukemia. March 2018 44. A. Daher, G. Maalouf, C. Irani. When intravenous immunoglobulins improve a chronic diarrhea . Revue de Medecine Interne March 2018 45. Irani C, Adib S, Halaby G, Sibai A. Obesity/overweight and asthma control in LEBANESE adults: a cross-sectional study.BMC Public Health 2019 Jun 17;19(1):769 46. Irani C, Hallit S, Mouzannar M, Salameh P. Aeroallergen sensitization and upper respiratory allergies among patients living in rural and urban areas: Real-life exploration of the hygiene hypothesis. WAO J 2019, sept 30;12(9) 47. Lee PY, Kellner ES, Huang Y et al. Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). J Allergy Clin Immunol. 2020 Jan 13. pii: S0091-6749(20)30030 48. Maalouly G, Hajal J, Saliba Y et al. Beneficial role of simvastatin in experimental autoimmune myositis. Int Immunopharmacol. 2019 Dec 18;79:106051 49. Carla Irani, Souheil Hallit, Stephanie Daccache, Pascale Salameh The use of Omalizumab in Severe Allergic asthma and Chronic Spontaneous Urticaria: real-life experience Journal of Allergy and Clinical Immunology,Feb 2020; Vol. 145, Issue 2, AB34 50. Tawil G, Tawil P, Irani C. Zirconium Implant as an Alternative to Titanium Implant in a Case of Type IV Titanium Allergy: Case Report. Int J Oral Maxillofac Implants. 2020 May/Jun;35(3):639-644 51. Klimek L, Jutel M, Akdis C, Bousquet J, Akdis M, Bachert C, Agache I, Ansotegui I, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Chivato T, Cruz AA, Czarlewski W, Giacco SD, Du H, Fonseca JA, Gao Y, Haahtela T, Hoffmann-Sommergruber K, Ivancevich JC, Khaltaev N, Knol EF, Kuna P, Larenas-Linnemann D, Melen E, Mullol J, Naclerio R, Ohta K, Okamoto Y, O'Mahony L, Onorato GL, Papadopoulos NG, Pawankar R, Pfaar O, Samolinski B, Schwarze J, Toppila-Salmi S, Shamji MH, Ventura MT, Valiulis A, Yorgancioglu A, Matricardi P, Zuberbier T; ARIA-MASK study group( corporate author). Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI statement. Allergy. 2020 Apr 24. 52. Bousquet J, Akdis C, Jutel M, Bachert C, Klimek L, Agache I, Ansotegui IJ, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Chivato T, Cruz AA, Czarlewski W, Del Giacco S, Du H, Fonseca JA, Gao Y, Haahtela T, Hoffmann-Sommergruber K, Ivancevich JC, Khaltaev N, Knol EF, Kuna P, Larenas-Linnemann D, Mullol J, Naclerio R, Ohta K, Okamoto Y, O'Mahony L, Onorato GL, Papadopoulos NG, Pfaar O, Samolinski B, Schwarze J, Toppila-Salmi S, Teresa Ventura M, Valiulis A, Yorgancioglu A, Zuberbier T; ARIA-MASK study group(corporate author). Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement. Allergy. 2020 Mar 31 53. Carla Irani, Souheil Hallit, Marilyn Karam, Candie Jammal, Martine Kai, Pascale Salameh. Overview of atopic dermatitis in a Lebanese population: A cross-sectional study. EAACI 2020 54. Samah Tawil, Carla Irani, Riwa Kfoury et al. The Arabic Urticaria Activity Score and Chronic Urticaria Quality of Life Questionnaire: validation and correlations. Int J Dermatol. 2020, Aug;59(8):893-901 55. Incorvaia C, Al-Ahmad M, Ansotegui I, et al. Personalized Medicine for allergy treatment: allergen immunotherapy still a unique and unmatched model [published online ahead of print, 2020 Sep 1]. Allergy. 56. Rouadi PW, Idriss SA, Naclerio RM et al. Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD). World Allergy Organ. Journal 2020 Oct;13(10) 57. Carla Irani, Angela Hacksu. Grains of Wisdom: Transgenic Rice for Oral Allergen Immunotherapy in Japanese Cedar Pollen-Allergic Patients. Int Arch Allergy Immunol.2020, Dec 15, 1-3 58. Bousquet J, Agache I, Blain H, Jutel M,et al Management of anaphylaxis due to COVID-19 vaccines in the elderly. Allergy. 2021 Apr 2. doi: 10.1111/all.14838. Epub ahead of print. PMID: 33811358. 59. Tawil S, Irani C, Kfoury R, Abramian S, Salameh P, Weller K, Maurer M, Ezzedine K. Assessment of urticaria using a self-reported diagnosis tool (SRUD): a multicenter validation study. J Eur Acad Dermatol Venereol. 2021 Apr 60. Aghamohammadi A, Rezaei N, Yazdani R, Delavari S, Kutukculer N, Topyildiz E, Ozen A, Baris S, Karakoc-Aydiner E, Kilic SS, Kose H, Gulez N, Genel F, Reisli I, Djenouhat K, Tahiat A, Boukari R, Ladj S, Belbouab R, Ferhani Y, Belaid B, Djidjik R, Kechout N, Attal N, Saidani K, Barbouche R, Bousfiha A, Sobh A, Rizk R, Elnagdy MH, Al-Ahmed M, Al-Tamemi S, Nasrullayeva G, Adeli M, Al-Nesf M, Hassen A, Mehawej C, Irani C, Megarbane A, Quinn J; MENA-I. E. I. Study Group, Maródi L, Modell V, Modell F, Al-Herz W, Geha RS, Abolhassani H. Consensus Middle East and North Africa Registry on Inborn Errors of Immunity. J Clin Immunol. 2021 May 29. 61. Tawil S, Irani C, Kfoury R, Abramian S, Salameh P, Weller K, Maurer M, Ezzedine K. Assessment of urticaria using a self-reported diagnosis tool (SRUD): a multicentre validation study. J Eur Acad Dermatol Venereol. 2021 Oct;35(10) 62. Sakakini J, Irani C, Bikai R, Sahyoun G, Hallit S, Salameh P, Dano D. Prevalence of Food Allergy among Schoolchildren in Lebanon. Int Arch Allergy Immunol. 2022 63. El-Sayed ZA, El-Ghoneimy DH, Ortega-Martell JA, Radwan N, Aldave JC, Al-Herz W, Al-Nesf MA, Condino-Neto A, Cole T, Eley B, Erwa NHH, Espinosa-Padilla S, Faria E, Rosario Filho NA, Fuleihan R, Galal N, Garabedian E, Hintermeyer M, Imai K, Irani C, Kamal E, Kechout N, Klocperk A, Levin M, Milota T, Ouederni M, Paganelli R, Pignata C, Qamar FN, Quinti I, Qureshi S, Radhakrishnan N, Rezaei N, Routes J, Singh S, Siniah S, Abdel-Hakam Taha I, Tanno LK, Van Dort B, Volokha A, Sullivan K. Allergic manifestations of inborn errors of immunity and their impact on the diagnosis: A worldwide study. World Allergy Organ J. 2022 Jun 17;15(6):100657 64. Tawil S, Irani C, Kfoury R, Abramian S, Salameh P, Weller K, Maurer M, Ezzedine K. Association of Chronic Urticaria with Psychological Distress: A Multicentre Cross-sectional Study. Acta Derm Venereol. 2023 Feb 14;103 65. Wajdi Abi Saleh1 , Zuhair Alameh2 , Zeina Aoun Bacha3* , Joudy Bahous4 , Pierre Bou Khalil5 , Zahia Chahine7 , Hassan Chami5,6, Georges Dabar3 , Hassan Dheiny8 , Alfred Dib9 , Dany farhat10, Carla Irani11, Georges Juvelekian4 , Nadim Kanj5 , Bassam Mansour12, Moussa Riachi3 , Mirna Waked4 , Mohamad Yassine10, Carole Youakim13, Salah Zeinedine5 and Fares . PRevalence of the Eosinophilic Phenotype Among SeveRE asthma patients in Lebanon: results of the PREPARE study. Allergy Asthma Clin Immunol 19, 80 (2023) 66. Dagher J, Antonios D, Chollet-Martin S, de Chaisemartin L, Pallardy M, Azouri H, Irani C. Drug-induced hypersensitivity reactions in a Lebanese outpatient population: A decade-long retrospective analysis (2012-2021). J Allergy Clin Immunol Glob. 2023 Sep 17;3(1):10016 67. Maurer M, Abuzakouk M, Al-Ahmad M, Al-Herz W, Alrayes H, Al-Tamemi S, Arnaout R, Binghadeer H, Gutta R, Irani C, Mobayed H, Nasr I, Shendi H, Zaitoun F. Consensus on diagnosis and management of Hereditary Angioedema in the Middle East: A Delphi initiative. World Allergy Organ J. 2022 Dec 24;16(1):100729. 68. Maurer M, Ensina LF, Gimenez-Arnau AM, Sussman G, Hide M, Saini S, Grattan C, Fomina D, Rigopoulos D, Berard F, Canonica GW, Rockmann H, Irani C, Szepietowski JC, Leflein J, Bernstein JA, Peter JG, Kulthanan K, Godse K, Ardusso L, Ukhanova O, Staubach P, Sinclair R, Gogate S, Thomsen SF, Tanus T, Ye YM, Burciu A, Barve A, Modi D, Scosyrev E, Hua E, Letzelter K, Varanasi V, Patekar M, Severin T; PEARL-1 and PEARL-2 trial investigators. Efficacy and safety of ligelizumab in adults and adolescents with chronic spontaneous urticaria: results of two phase 3 randomised controlled trials. Lancet. 2023 Nov 23:S0140-6736(23)01684-7. 69. Turner PJ, Ansotegui IJ, Campbell DE, Cardona V, Carr S, Custovic A, Durham S, Ebisawa M, Geller M, Gonzalez-Estrada A, Greenberger PA, Hossny E, Irani C, Leung ASY, Levin ME, Muraro A, Oppenheimer JJ, Ortega Martell JA, Pouessel G, Rial MJ, Senna G, Tanno LK, Wallace DV, Worm M, Morais-Almeida M; WAO Anaphylaxis Committee and WAO Allergen Immunotherapy Committee. Updated grading system for systemic allergic reactions: Joint Statement of the World Allergy Organization Anaphylaxis Committee and Allergen Immunotherapy Committee. World Allergy Organ J. 2024 Feb 10;17(3):100876. 70. https://www.pathlms.com/wao/courses/1890: urticaria modules 71. Managing of Asthma with with Allergic rhinitis in Adults 2016 http://www.worldallergy.org/modules/course/view.php?id17