(+961) 1 421 000 ext 6820 jad.chemali@usj.edu.lb
Dr. Jad N. Chémali is a researcher and educator in the field of medical research, specializing in cancer research. Originally from Lebanon, he left his country at a young age to pursue his studies in France, where he found an environment conducive to his scientific ambitions. Academic Background - Bachelor’s degree in Biochemistry and Molecular Biology from Paul Sabatier University, Toulouse III, France. - Master’s degree in Biochemistry and Biotechnology from Paul Sabatier University, Toulouse III, France. - Master 2 in Chemistry for Health, specializing in gene therapy and drug design, from Paul Sabatier University, Toulouse III, and the National Polytechnic Institute of Toulouse, France. - PhD in Chemistry-Biology-Health, focusing on the synthesis of anticancer molecules for photodynamic therapy, from Paul Sabatier University, Toulouse III, France. Career and Contributions After earning his PhD, Dr. Chémali pursued postdoctoral research at the IMRCP laboratory (CNRS, UMR 5623) in Toulouse for two years. He then returned to Lebanon to continue his cancer research, particularly focusing on drug repurposing. This approach aims to identify existing medications approved for other diseases that could be effective against cancer, thereby reducing the time and cost of developing new treatments. Research and Teaching Activities In addition to his research, Dr. Chémali is a dedicated educator at Saint Joseph University of Beirut (USJ), where he teaches at the Faculty of Medicine and the Faculty of Sciences. He is currently the director of the Cancerology and Carcinogenic Agents Laboratory at the USJ Faculty of Medicine. His research focuses on: - Developing personalized treatments for cancer patients, aiming to optimize therapies based on the individual characteristics of each patient. - Studying carcinogenic agents and their impact on the early onset of certain cancers in Lebanon. - Investigating the root causes of cancer, exploring potentially unknown phenomena that could contribute to the disease. Vision and Impact Dr. Chémali is committed to fighting cancer and is constantly seeking new and effective solutions to combat this disease. His holistic approach and willingness to explore innovative therapeutic options reflect his dedication to the field of cancer research.
Highest degree : PhD in Chemistry-Biology-Health - Université Paul-Sabatier (Toulouse III) - France
Degrees | University | Country | Year |
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Chemistry-Biology-Health | Université Paul-Sabatier (ToulouseIII) | France | 2013 |
Chemistry- Biologie -Health | Université Paul-Sabatier (ToulouseIII) | France | 2008 |
Biotechnology and Biochemistry | Université Paul-Sabatier (ToulouseIII) | France | 2007 |
Biochemistry and Molecular Biology | Université Paul-Sabatier (ToulouseIII) | France | 2006 |
Metabolic Biochemistry Structural Biochemistry Chemical Contaminants Cancer Reproductive Biology Cell Biology Nutrition Metabolism of the Healthy Human Biochemistry of Cancer Cells Drug Repurposing in Oncology
Experience in University Teaching Outside USJ | Country | Institution | Start Date | End Date |
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Courses: “General Biology”, “Human Physiology” and “Food Cancer Risks” | Lebanon | American University College of Technology (AUT) | 26/09/2016 | 20/06/2017 |
Teaching Assistant: Photodynamic Therapy for Cancer | France | Université Paul-Sabatier (ToulouseIII) | 01/02/2013 | 01/03/2013 |
Teaching Assistant: Applications of Gene Therapy | France | Université Paul-Sabatier (ToulouseIII) | 01/10/2012 | 01/11/2012 |
Professional Experience | Organization | Start date | End date |
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Medical researcher | USJ | 01/10/2016 | 01/01/2024 |
Postdoctoral Training: Medical Molecular Biology: Saint Joseph University, Beirut, Lebanon | USJ | 01/10/2015 | 01/10/2016 |
Temporary researcher | IMRCP Laboratory Toulouse III | 01/10/2012 | 01/10/2014 |
Medecine and Health
The laboratory focuses on developing innovative strategies to combat cancer. This includes the repurposing of FDA-approved drugs to find effective combinations against various forms of cancer. A personalized medicine approach is also implemented to determine the best treatment for each patient using biopsies ex vivo tests. Additionally, the laboratory is interested in studying the risk of contaminants causing cancer in the Lebanese population, particularly aflatoxin B1. There is also a focus on studying arsenic its impact on the risk of breast ovarian cancer in women carrying BRCA1 BRCA2 mutations. The laboratory is also interested in studying other causes of cancer to identify the true triggering factors.
-Synthesis, physico-chemical properties, cellular penetration photodynamic antiproliferative activity on MCF7 breast cancer cell line of new rose bengal-estradiol conjugates. Jad Chemaly, Patricia Vicendo, Naram El-Akra Jean-Pierre Souchard. Photodiagnosis Photodynamic Therapy. DOI: 10.1016/j.pdpdt.2017.01.122. -Role of intercalation redox potential in DNA photosensitization by ruthenium (II) polypyridyl complexes: assessment using DNA repair protein tests. Etienne Gicquel, JeanPierre Souchard, Fay Magnuson, Jad Chemali, Patrick Calsou Patricia Vicendo. Photochem. Photobiol. Sci., DOI: 10.1039 / C3PP50070E. -Tratrat C, Petrou A, Fesatidou M, Haroun M, Athina G, Venugopala K, Sreeharsha N Chemali Jad. 5-Membered Heterocyclic Compounds as Antiviral Agents. Curr Top Med Chem. 202323(7):520-538. doi: 10.2174/1568026623666230325153927. PMID: 37254567. Jad Chemaly, Patricia Vicendo, Naram El-Akra Jean-Pierre Souchard, “Synthesis, physico-chemical properties, cellular penetration photodynamic antiproliferative activity on MCF7 breast cancer cell line of new rose bengal-estradiol conjugates”. Joint Congress of the French and Italian Photochemists and Photobiologists. Bari, Italy, September 19-22, 2016. Jad Chemali, El-Akra Naram, Vicendo Patricia, Souchard Jean Pierre, “Synthesis, physicochemical properties, cellular penetration and photodynamic antiproliferative activity on MCF7 breast cancer cell line of new rose bengal-estradiol conjugates”. International symposium on photodynamic therapy in clinical practice. October 24-28, 2016, Nancy, France. Jad Chemali, Naram El-Akra, Ariel Noirot, Jean-Charles Faye, Patricia Vicendo, and Jean Pierre Souchard, “Photocytotoxic active vectorization probes for photodynamic therapy by targeting the Estradiol nuclear receptor”. December 12-13, 2012. Toulouse, France.